The Effectiveness of Sea Lettuce (Ulva Lactuca) Water Extract from Aceh Waters as an Anti-Obesity

Rinawati Rinawati, Sri Wahyuni Muhsin

Abstract


Obesity is a condition of weight excess above average weight. Obesity can happen due to calories continuing into the body without being offset by physical activity. This study aims to determine the effectiveness of the water extract of Ulva Lactuca against weight loss in obese mice. type of research used is laboratory experiments using the design posttest only control group design research. we grouped into 7 groups, namely: normal Control, Positive Control, Treatment Control, P1= the group of obese mice + extract 300 mg/kg, P2= the group of obese mice + extract 400 mg/kg, P3= the group of obese mice + extract 500 mg/kg P4=the group of obese mice + orlistat.The Aqueous Extract of Ulva Lactuca has not been able to lose obese mice for 28 days of treatment. Normal mice in treatment of the Extract did not show changes in body weight


Keywords


Ulva Lactuca; Obesity; Weight

Full Text:

PDF

References


Arbi B, ma'ruf W. F and Ramadan (2016) Activity of the Bioactive Compounds Sea Lettuce (Ulva Lactuca) As an Antioxidant In Fish Oil. Journal of Fisheries Science and Technology. 12 (1): 12-18.

Ardiansyah, S. A, Hidaya, D. S and Simbolon, N, S. (2018). Activity test Antiobesitas of the Ethanol Extract of the Leaves of Malacca (Phyllanthus Emblica L) Against the White Male Rats Strain Wistar. Indonesian Journal of Pharmaceutical Science and Technology. 7(1): 18-29

Bansal, B. Agam and Yasir Al Khalili. (2020). Orlistat. Treasure Island: StatPearls Publishing

BelHadj, S., Hentati, O., Elfeki, A., & Hamden, K. (2013). Inhibitory activities of Ulva Lactuca polysaccharides on digestive enzymes related to diabetes and obesity. Archives of physiology and biochemistry, 119(2), 81-87.

Dominiquez, H and Loret, E. P. (2019). Ulva lactuca , A Source of Troubles and Potential Riches.

Hastuti, P. (2019). Genetic Obesity. Yogyakarta: Gadjah Mada University Press.

Hermawan, D., Muhani,N., Sari, N., Arisandi, S., Widodo., Lubis, M. Y., Kristina, T., Umdiyana L., Firdaus, A. A. (2020). Know Your Obesity. Yogyakarta: Andi

Kandinasti, S, and Farapti (2018) Obesity: is it Important to pay attention to the Consumption of Food at the End of the Week? Obesity: is it Important to pay attention to food consumption at the End of the Week? Literature appreciate. Amerta Nutr 307-316

Kemenkes RI. (2012). Guidelines for preventing and controlling overweight and obesity in school children, the Ministry of Health of Indonesia.

KEMENKES. (2011). Decree of the Minister of Health Number: 1995/MENKES/SK/XII/2010 on Standard Anthropometric Assessment of the Nutritional Status of Children

Kepel, R.. Mantiri, S. M. H., Rumengan, A and Nasprianto. (2018). Biodiversity of Macroalgae in Coastal Waters of the Village Blongko, District Sinonsayang, Kabupaten Minahasa Selatan. Jurnal Ilmiah Platax. 6(1): 174-187

Lordan, S.; Ross, R. P.; Stanton, C. (2011). Marine Bioactives As Functional Food Ingredients: Potential To Reduce The Incidence Of Chronic Diseases. Mar. Drugs. 9(1):1056-110

Masrul. (2018). The Obesity epidemic and its Impact On the Health Status of the Community and the Social Economy of the Nation. Magazine Of Medicine Andalas. 41(3): 152-162

Mariska, I. (2013). Secondary metabolites: the Path of the Formation and its Usefulness. (http://biogen.litbang.deptan.go.id). Accessed 16 September 2020

Misnadiarly. (2007). Obesity As A Risk Factor Of Several Diseases. Jakarta: Yayasan Pustaka Torch.

Moyers, B. (2005). Medications as Adjunct Therapy for Weight Loss: Approved and Off-Label Agents in Use. Research, Volume 105:(6).

Patonah, Susilawati, E and Riduan, A. (2017). Activity Antiobesitas Extract of the Leaves Katuk (Sauropus androgynus L. Merr) In a Model of Murine Obesity. Pharmacy. 4(2): 137-152.

Pertiwi , P. A and Widyaningsih, W. (2005). The effect of Ethanol Extract of Green Algae (Ulva Lactuca L) On the Activity of alanine aminotransferase-AST In Rats. Trad. med. 20(1):1-6

Daughter, Cynthia Astiti. (2016). The Effect of Ethanolic Extract of the Leaves of Red Spinach (Amaranthus tricolor L) standardized to body mass index and blood glucose levels in Sprague-Dawley rats given a high-fat diet preventive obesity". Pharmacy. Vol.13.

Rusmini, H, Marlina, D and Lestari, P. (2019). The influence of Flavonoids In the Extract of Cucumber (Cucumis sativus L) On Total Blood Cholesterol Levels of Mice (Mus musculus L) who consume Fast Food. Journal of Medical Science and Health. 6(3): 166-175

Saada, H and Nurhasanawati. (2015). Comparison of Ethanol and Water In the Manufacture of Extracts of Onion Bulbs Tiwai (Eleutherine Americana Merr) Using the Maceration Method. Jurnal Ilmiah Manuntung. 1(2):149-153

Salamah. N., Widyaningsih, W, Izzati, I and Susanti, H. (2015). The activity of free Radical scavengers Ethanol Extract of green algae Spirogyra sp and Ulva Lactuca. 13(2): 145-150.

Susantiningsih, T. (2015). Obesity and Oxidative Stress. Journal Of Health Unila. 5(9): 89

Swinburn, B., Caterson, I., Seidell, J. C. & James, W. P. T. (2004) Diet, Nutrition, and Prevention Of Excess Weight Gain and Obesity. Public Health Nutrition. 7(1):123-146

Silva M, Vieira L, Almeida AP, Kijjoa A. (2013). The Marine Macroalgae of The Genus Ulva: Chemistry, Biological Activities, and Potential Applications. Oceanography. 1(1):1-6

Ulaan G,A, K, o, A and Rotinsulu, H. (2019). The Antioxidant Activity test of Ethanol Extract of Algae Ulva Lactuca Using DPPH (1,1-diphenyl-2-picrylhydrazyl). Pharmacon. 8(3):535-541

Widyaningsih, W and Salama, N. (2015). The effect of ethanol Extract of Green Algae ( Ulva Lactuca L) Against Body Weight and Triglyceride Levels Male Rats were Given a High Fat Diet. Pharmacia 5(2):191-198

Widyaningsih, W., Salama, N and Maulida, F. Q. (2016). The Effect of Ethanolic Extract Of Green Algae (Ulva Lactuca L) On Blood Cholesterol Levels In Male Fats By High Fat Diet. Medical Journal Of Indonesia. 7(5):181-186

Widyaningsih , W and Afdaliah S. N. (2020). The effect of Gastroprotective Ethanol Extract of Green Algae (Ulva Lactuca) In the Rat Stomach. Indonesian Journal Of Pharmaceutical Science and Technology. 7(2):7-80

Rinawati. (2015). The characterization of the Anatomy and the Effect of the Extract Decoction of the Leaves of Tithonia diversifolia (hems.) A. Gray on blood glucose levels of White Rats (Rattus norvegicus Berkhout, 1769). Thesis. Universitas Gadjah Mada. Yogyakarta.

Rinawati, Nursia, L. E, Muhsin, S. W and Siregar, S. M. (2020). The influence of Water Extract of Sea Lettuce (Ulva Lactuca) On Body Weight In Diabetic Rats. Stigma.13(1):39-46.

Zulfadhli and Rinawati. (2018). The potential of Sea Lettuce (Ulva Lactuca) As Antifungi In Infection Control Saprolegnia and Achyla On Fish farming Kerling (Tor sp). Journal of fisheries of the tropical. 5(2):183-185




DOI: https://doi.org/10.35308/j-kesmas.v9i1.5238

Refbacks

  • There are currently no refbacks.



Managed by Fakultas Kesehatan Masyarakat

Published by Universitas Teuku Umar
Website: http://jurnal.utu.ac.id/jkesmas
Email: jkemas@utu.ac.id

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.